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  • icon Our Methods
  • icon Recent Presentations
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imageOur EffortsWe are studying the effects of post-translational modification on membrane proteins involved human diseases. We use in vitro glycosylation to study the changes that occur when a sugar group is attached to a protein. Read More
imageOur Methods We use both solution and solid-state NMR to determine the structure, dynamics and interactions of membrane proteins in lipid enviroments that resemble the membranes of cells. Read More
imageRecent Presentations The Cook Lab had the pleasure of hosting an REU student this summer. Emily Knight carried out research on Sarcoglycan and presented a poster at the REU Symposium at the conclusion of the 10-week program. Read More
imageNews The Cook Lab had two undergraduate recipients of scholarships for the 2016 year. Michael Jamaleddine received the Wentz Award while Micah Gillezeau was awarded an Undergrad Research Scholarship. Read More
 
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Take a virtual tour of our lab in the Henry Bellmon Research Center

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Outreach

Education is an important part of making sure we have future scientists. If you have an outreach need let us know about it.

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Become a Cowboy

Learn more about our graduate program at Oklahoma State University

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The goal of our lab is to use multidisciplines of science; chemistry, biology, biochemistry, and physics, to improve the quality of life for mankind. We believe that we can make a difference with our research.

 

 

 

 

 

 

 

 

 

Selected Publications

Three-dimensional structure and interaction studies of hepatitis C virus p7 in 1,2-dihexanoyl-sn-glycero-3-phosphocholine by solution nuclear magnetic resonance Biochemistry, 2013, 52:5295-303 Cook GA, Dawson LA, Tian, Y, Opella, SJ

Abstract

'q-Titration' of long-chain and short-chain lipids differentiates between structured and mobile residues of membrane proteins studied in bicelles by solution NMR spectroscopy J Magn Reson, 2012 214:111-8 Son WS, Park SH, Nothnagel HJ, Lu GJ, Wang Y, Zhang H, Cook GA, Howell SC, Opella SJ

Abstract

Nanodiscs versus macrodiscs for NMR of membrane proteins Biochemistry, 2011, 50:8983-5 Park SH, Berkamp S, Cook GA, Chan MK, Viadiu H, Opella SJ

Abstract

Structural and biophysical properties of a synthetic channel-forming peptide: designing a clinically relevant anion selective pore Biochim Biophys Acta, 2012, 1818:1039-48 Bukovnik U1, Gao J, Cook GA, Shank LP, Seabra MB, Schultz BD, Iwamoto T, Chen J, Tomich JM

Abstract